Cancer Zosuquidar Trihydrochloride

Cancer Zosuquidar Trihydrochloride

Cancer Zosuquidar Trihydrochloride

Some extra aspects of killing cancer cells is mentioned by the following:

  1. You can conclude that, zosuquidar trihydrochloride may help kill cancer cells that are resistant to anticancer drugs.[1] Cancer is a term for diseases in which abnormal (i.e., deviant) cells divide without control and can invade nearby tissues. Cancer cells can also spread to other parts of the body (i.e., corpus) through the blood (i.e., haema) and lymph (i.e., lympha) systems. There are several main (i.e., hand) types of cancer. Carcinoma is a cancer that begins in the skin (i.e., cutis) or in tissues that line (i.e., linea) or cover internal (i.e., internus) organs. Sarcoma is a cancer that begins in bone (i.e., os), cartilage (i.e., cartilago, or chondrus), fat (i.e., adipose tissue), muscle (i.e., musculus, or see musculus), blood vessels, or other connective or supportive tissue. Leukemia (i.e., leukocytic sarcoma) is a cancer that starts in blood-forming tissue such as the bone marrow (i.e., medulla ossium), and causes large numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and multiple myeloma (i.e., multiple myelomatosis, or myelomatosis multiplex) are cancers that begin in the cells of the immune system. Central nervous system (i.e., systema nervosum) cancers are cancers that begin in the tissues of the brain and spinal (i.e., rachial, or rachidial) cord (i.e., fasciculus, or funiculus). Also called malignancy. Zosuquidar trihydrochloride is a substance (i.e., substantia, or matter) being studied in the handling of cancer. Zosuquidar trihydrochloride may help kill cancer cells that are resistant to anticancer drugs. As well called LY335979.
  2. Apparently, it also blocks enzymes needed for cell growth and may kill cancer cells.[2]

In addition, we are able to increase the risk for pursuing findings with respect to Cancer Zosuquidar Trihydrochloride :

  • Apparently, it is also used together with other drugs to treat multiple myeloma and to prevent bone fractures and reduce bone pain in people who have cancer that has spread to the bone.[1] Multiple myeloma is a type of cancer that begins in plasm (i.e., plasma) cells (white (i.e., albicans) blood cells that produce antibodies). Likewise called Kahler disease, myelomatosis, and plasma (i.e., blood plasma) cell myeloma (i.e., multiple myeloma). Myeloma, cancer that arises in plasm cells, a type of white blood cell.
  • It might seem apparant that, a drug used to reduce heart (i.e., cor, or coeur) damage in women given doxorubicin (i.e., adriamycin) for breast (i.e., mamma, or teat) cancer that has spread.[1] Breast cancer, cancer that forms in tissues of the breast, usually the ducts (tubes that carry milk (i.e., strip, or lac) to the nipple (i.e., papilla mammae, or mammilla)) and lobules (glands that make milk). It occurs in both men and women, although male (i.e., masculine) breast (i.e., mamma masculina, or mamma virilis) cancer is rare. Breast, glandular (i.e., glandulous) organ located on the chest (i.e., pectus). The breast is made up of connective tissue (i.e., interstitial tissue, or supporting tissue), fat, and breast tissue that contains the glands that can make milk. Also called mammary gland (i.e., glandula mammaria, or lactiferous gland).
  • For instance, monoclonal antibodies are made in the laboratory and can locate and bind to substances in the body, including cancer cells.[2]
  • It looks that, zibotentan may block malignant neoplastic disease cell emergence.[2] Zibotentan is a substance being studied in the handling of some types of cancer. Zibotentan may block cancer cell growth. It is a type of endothelin-A sense organ antagonist.
  • It’s been found that, a drug that is used to care for certain types of non-little cell lung (i.e., pulmo) cancer and is being studied in the treatment of other types of cancer.[3] Lung, one of a dyad (i.e., diad) of organs in the chest that supplies the organic structure (i.e., structura) with oxygen, and removes carbon dioxide from the body. Lung cancer, cancer that forms in tissues of the lung, commonly in the cells lining air (i.e., ventilate) passages. The two main types are little cell lung cancer and non-little cell lung cancer. These types are diagnosed based on how the cells appear under a microscope.
  • Finally, for instance, a substance that is used to surpress asthmra symptoms and that is being studied in the prevention of lung cancer is discussed here.[3] Prevention is in medicine, action taken to decrease the chance of getting a disease or condition. For example, cancer prevention includes avoiding risk factors (such as smoking, obesity (i.e., adiposity, or corpulence), lack of exercise, and radiation (i.e., radiatio) exposure) and increasing protective factors (such as getting regular physical activity, staying at a healthy weight, and having a healthy diet). Asthma is a chronic disease in which the bronchial airways in the lungs become narrowed and swollen, making it difficult to take a breath. Symptoms include wheezing, coughing, constriction (i.e., constrictio) in the chest, shortness of breath, and rapid breathing (i.e., pneusis). An attack may be brought on by pet hair (i.e., pilus), dust, smoke, pollen, model, exercise, cold (i.e., frigid) air, or stress.

Terminology


Mammary gland

the potential and active compound, alveolar, mostly merocrine (with possible apocrine components) milk-secreting gland lying within the breast; it comprises 1524 lobes, each consisting of many lobules, separated by adipose tissue and
fibrous septa; the parenchyma of the resting postpubertal female gland consists of ducts; the alveoli develop only during pregnancy and remain active until weaning; normally, the gland remains rudimentary (undistinguishable from its childhood state) in men


Lymph

A clear, transparent, sometimes faintly yellow and slightly opalescent fluid that is collected from the tissues throughout the body, flows in the lymphatic vessels (through the lymph nodes), and is eventually added to the venous blood circulation. Lymph consists of a clear liquid portion, varying numbers of white blood cells (chiefly lymphocytes), and a few red blood cells


Cord

  1. In anatomy, any long ropelike structure, composed of several to many longitudinally oriented fibers, vessels, ducts, or combinations thereof.
  2. In histopathology, a line of tumor cells only one cell in width


Marrow

  1. A highly cellular hemopoietic connective tissue filling the medullary cavities and spongy epiphyses of bones; it becomes predominantly fatty with age, particularly in the long bones of the limbs.
  2. Any soft gelatinous or fatty material resembling the marrow of bone.


Myelomatosis

A disease characterized by the occurrence of myeloma in various sites.


Spinal

  1. Relating to any spine or spinous process.
  2. Relating to the vertebral column


Mammilla

A small rounded elevation resembling the female breast


Nervous system

the entire nerve apparatus, composed of a central part (the brain and spinal cord) and a peripheral part (the cranial and spinal nerves, autonomic ganglia, plexuses and peripheral nerves)


Adipose

Denoting fat.


Leukocytic

Pertaining to or characterized by leukocytes


Immune system

an intricate complex of interrelated cellular, molecular, and genetic components that provides a defense, the immune response, against foreign organisms or substances and aberrant native cells.


Glandular

Relating to a gland


Brain

That part of the central nervous system contained within the cranium.


Monoclonal

In immunochemistry, pertaining to a protein from a single clone of cells, all molecules of which are the same; in the case of Bence Jones protein, the chains are all ???? or ????.


Medulla

Any soft marrowlike structure, especially in the center of a part


Adiposity

Excessive accumulation of lipids in a site or organ


Cartilage

A connective tissue characterized by its nonvascularity and firm consistency; consists of cells (chondrocytes), an interstitial matrix of fibers (collagen), and ground substance (proteoglycans). There are three kinds of cartilage hyaline cartilage, elastic cartilage, and fibrocartilage. Nonvascular, resilient, flexible connective tissue found primarily in joints, the walls of the thorax, and tubular structures (larynx, air passages, and ears); makes up most of the skeleton in early fetal life, but is slowly replaced by bone. For a gross anatomic description, see cartilago and its subentries


Pilus

A fine filamentous appendage, somewhat analogous in function to the flagellum, which occurs on some bacteria. Although they can be chemically similar to flagella, pili consist only of protein and are shorter, straighter, and more numerous. Specialized pili (F pili, I pili, and other conjugative pili) seem to mediate bacterial conjugation and bacterial attachment to host cells during the infective process


Antagonist

Something opposing or resisting the action of another; certain structures, agents, diseases, or physiologic processes that tend to neutralize or impede the action or effect of others.


Leukemia

Progressive proliferation of abnormal leukocytes found in hemopoietic tissues, other organs, and usually in the blood in increased numbers. Leukemia is classified by the dominant cell type, and by duration from onset to death. This occurs in acute leukemia within a few months in most cases, and is associated with acute symptoms including severe anemia, hemorrhages, and slight enlargement of lymph nodes or the spleen. The duration of chronic leukemia exceeds one year, with a gradual onset of symptoms of anemia or marked enlargement of spleen, liver, or lymph nodes


Breath

  1. The respired air.
  2. An inspiration.


Papilla

Any small, nipplelike process


Myeloma

  1. A tumor composed of cells derived from hemopoietic tissues of the bone marrow.
  2. A plasma cell tumor.


Neoplastic

Pertaining to or characterized by neoplasia, or containing a neoplasm.


Mammary

Relating to the breasts.


Ventilate

To aerate, or oxygenate, the blood in the pulmonary capillaries


Constriction

  1. A normally or pathologically contracted or narrowed portion of a structure.
  2. The act or process of binding or contracting, becoming narrowed; the condition of being constricted. squeezed.
  3. A subjective sensation of pressure or tightness, as if the body or any body part were tightly bound or squeezed


Malignancy

The property or condition of being malignant.


Chronic

  1. Referring to a health-related state, lasting a long time.
  2. Referring to exposure, prolonged or long-term, sometimes meaning also low intensity.
  3. The U.S. National Center for Health Statistics defines a chronic condition as one persisting 3 months or longer.


Lymphoma

Any neoplasm of lymphoid or reticuloendothelial tissues; in general use, synonymous with malignant lymphoma; present as apparently solid tumors composed of cells that appear primitive or resemble lymphocytes, plasma cells, or histiocytes. Lymphomas appear most frequently in the lymph nodes, spleen, or other normal sites of lymphoreticular cells; may invade other organs or manifest as leukemia. Lymphomas are now classified by histology, immunophenotype, and cytogenetic analysis, according to cell of orgin (B or T cells) and degree of maturation. The current World Health Organization (WHO) classification of lymphoid neoplasms is based on the Revised European-American Lymphoma (REAL) classification and effectively replaces older schemes such as the Working Formulation and Rappaport classification, which were based solely on morphology.


Deviant

  1. Denoting or indicative of deviation.
  2. A person exhibiting deviation, especially sexual


Masculine

Relating to or marked by the characteristics of the male sex or gender


Medicine

  1. A drug.
  2. The art of preventing or curing disease; the science
    concerned with disease in all its relations.
  3. The study and treatment of general diseases or those affecting the internal parts of the body, especially those not usually requiring surgical intervention.


Radiation

radiophobia.


Malignant

  1. occurring in severe form, and frequently fatal; tending to become worse and leading to an ingravescent course.
  2. In reference to a neoplasm, having the property of locally invasive and destructive growth and metastasis.


Plasma

  1. The proteinaceous fluid (noncellular) portion of the circulating blood, as distinguished from the serum obtained after coagulation.
  2. The fluid portion of the lymph.
  3. The fluid in which the fat droplets of milk are suspended.
  4. A ??????fourth state of matter?????? in which, owing to elevated temperature, atoms have broken down to form free electrons and more-or-less stripped nuclei; produced in the laboratory in connection with hydrogen fusion (thermonuclear) research.
  5. Highly ionized gas


Lung

One of a pair of viscera occupying the pulmonary cavities of the thorax, the organs of respiration in which blood is aerated. In humans, the right lung is slightly larger than the left and is divided into three lobes (an upper, a middle, and a lower or basal), whereas the left has but two lobes (an upper and a lower or basal). Each lung is irregularly conic, presenting a blunt upper extremity (the apex), a concave base following the curve of the diaphragm, an outer convex surface (costal surface), a generally concave inner or medial surface (mediastinal surface), a thin and sharp anterior border, and a rounded posterior border


Endothelin

A 21-amino acid peptide originally derived from endothelial cells. It is an extremely potent vasoconstrictor. Three different gene products have been identified, endothelin 1, endothelin 2, and endothelin 3; they are found in brain, kidney, and endothelium (endothelin 1), intestine (endothelin 2), and intestine and adrenal gland (endothelin 3).


Multiple myeloma

an uncommon disease that occurs more frequently in men than in women and is associated with anemia, hemorrhage, recurrent infections, and weakness. Ordinarily, it is regarded as a malignant neoplasm that originates in bone marrow and involves chiefly the skeleton, with clinical features attributable to the sites of involvement and to abnormalities in formation of plasma protein; characterized by numerous diffuse foci or nodular accumulations of abnormal or malignant plasma cells in the marrow of various bones (especially the skull), causing palpable swellings of the bones, and occasionally in extraskeletal sites; radiologically, the bone lesions have a characteristic punched-out appearance. The myeloma cells produce abnormal proteins in the serum and urine; those formed in any one example of multiple myeloma are different from other myeloma proteins, as well as from normal serum proteins, the most frequent abnormalities in the metabolism of protein being 1) the occurrence of Bence Jones proteinuria, 2) a great increase in monoclonal ????-globulin in the plasma, 3) the occasional formation of cryoglobulin, and 4) a form of primary amyloidosis. The Bence Jones protein is not a derivative of abnormal serum protein, but seems to be formed de novo from amino acid precursors


Doxorubicin

An antineoplastic antibiotic isolated from Streptomyces peucetius; also used in cytogenetics to produce Q-type chromosome bands


Interstitial

  1. Relating to spaces or interstices in any structure.
  2. Relating to spaces within a tissue or organ, but excluding such spaces as body cavities or potential space.


Diad

The transverse tubule and a terminal cisterna in cardiac muscle fibers


Corpus

  1. Any body or mass.
  2. The main part of an organ or other anatomic structure, as distinguished from the head or tail


Chondrus

The plant Chondrus crispus, Fucus crispus, or Gigartina mamillosa (family Gigartinaceae); a demulcent in chronic and intestinal disorders


Asthma

An inflammatory disease of the lungs characterized by (in most cases) reversible airway obstruction. Originally, a term used to mean ??????difficult breathing??????; now used to denote bronchial asthma.


Lac

Any whitish, milklike liquid


Nervous

  1. Relating to a nerve or the nerves.
  2. Easily excited or agitated; suffering from mental or emotional instability; tense or anxious.
  3. Formerly, denoting a temperament characterized by excessive mental and physical alertness, rapid pulse, excitability, often volubility, but not always fixity of purpose.


Lactiferous

Yielding milk.


Bronchial

Relating to the bronchi.


Dioxide

A molecule containing two atoms of oxygen, carbon dioxide, CO2.


Dyad

  1. A pair.
  2. In chemistry, a bivalent element, molecule, or ion.
  3. Two people in an interactional situation, patient and therapist, husband and wife.
  4. The double chromosome resulting from division in meiosis.
  5. Two units treated as one.
  6. A pair of cells resulting from the first meitotic division.
  7. The transverse tubule and a terminal cisterna in cardiac muscle cells


Connective tissue

the physical or functional supporting tissue of the animal body, a major constituent of which (in addition to various kinds of cells) is an extracellular matrix of ground substance, protein fibers, and structural glycoproteins; it is derived from the mesenchyme, which in turn is derived mainly from mesoderm; the many kinds of connective tissue may be classified according to cell-matrix proportion (loose vs. dense), arrangement of fibers (regular dense vs. irregular dense), fiber type (collagenous, elastic), embedded cell type (adipose, lymphoid, hemopoietic), degree of differentiation (mesenchymal, mucous), location (subcutaneous, periosteal, perichondrial), appearance (areolar, granulation), or nature of matrix (cartilaginous, osseous, or, in the cases of blood and lymph, liquid)


Heart

A hollow muscular organ that receives the blood from the veins and propels it into the arteries. In mammals it is divided by a musculomembranous septum into two halves right or venous and left or arterial each of which consists of a receiving chamber (atrium) and an ejecting chamber (ventricle)


Sarcoma

A connective tissue neoplasm, usually highly malignant, formed by proliferation of mesodermal cells.

Related Material

  1. Regional Cancer Care
  2. arch_dictionary
  3. Cancer Term Glossary

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