Cancer Risk Oral Mucositis

Cancer Risk Oral Mucositis

Cancer Risk Oral Mucositis

The following risk oral mucositis things show a top level of importance:

  1. It’s possible to assume that, you should ask your oncologist if there are any new drugs or protocols that you may be eligible for to reduce your risk of oral mucositis.[4] Oral, by or having to perform with the mouth (i.e., oral cavity (i.e., cavitas, or cavernous space), or ostium). Oncologist is a dr. who specializes in treating malignant neoplastic disease (i.e., illness, or morbus). Some oncologists specialise in a particular type (i.e., typus, or variation) of malignant neoplastic disease treatment. For instance, a radiation (i.e., radiatio) oncologist (i.e., radiotherapist) specializes in treating cancer with radiation. Cancer is a term for diseases in which abnormal (i.e., deviant) cells divide without control and can occupy nearby tissues. Cancer cells can also unfold to other parts of the body (i.e., corpus) through the blood (i.e., haema) and lymph (i.e., lympha) systems. There are several main (i.e., hand) types of cancer. Carcinoma is a cancer that begins in the tegument (i.e., integument, or integument) or in tissues that line (i.e., linea) or screen internal (i.e., internus) organs. Sarcoma is a cancer that begins in bone (i.e., os), cartilage (i.e., cartilago, or chondrus), adipose tissue (i.e., fat, or fatty tissue), muscle (i.e., musculus, or see musculus), blood vessels, or other connective or supportive tissue. Leukemia (i.e., leukocytic sarcoma) is a cancer that starts in blood-forming tissue such as the os marrow, and causes big numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and multiple myeloma (i.e., multiple myelomatosis, or myelomatosis multiplex) are cancers that start in the cells of the immune system. Central nervous scheme (i.e., schema) cancers are cancers that begin in the tissues of the brain and spinal (i.e., rachial, or rachidial) cord (i.e., fasciculus, or funiculus). Likewise called malignancy. Mucositis is a ramification of some cancer therapies in which the lining of the digestive (i.e., digestant) system becomes inflamed. Frequently
    seen as sores in the mouth.
  2. It appears to be that, numerous factors contribute to the peril of oral mucositis including those discussed here.[5]

In addition, we are able to increase the risk for pursuing findings with respect to Cancer Risk Oral Mucositis :

  • It would seem to be apparant that, a pleomorphism (i.e., polymorphism) in the 5,10 methylene-tetrahydrofolate reductase (i.e., reducing enzyme) (MTHFR) cistron C677 is discussed here.[1]
  • It would seem to be apparant that, t is a known genetic risk factor that can cause methotrexate (i.e., amethopterin) perniciousness and result in an increase in the severity of oral mucositis in patients treated with the drug.[1] Risk factor, something that increases the prospect of developing a disease. Some examples of risk factors for cancer are age, a family history of certain cancers, use of tobacco products, being exposed to radiation or certain chemicals, infection with certain viruses or bacteria, and certain genic changes. Genetic, inherited; having to execute with information that is passed from parents to offspring through genes in sperm (i.e., sperm cell, or spermatozoon) and egg cells. Methotrexate is a drug used to treat some types of malignant neoplastic disease, rheumatoid arthritis (i.e., articular rheumatism), and severe skin (i.e., cutis) conditions, such as psoriasis. Methotrexate stops cells from making Dna and may kill malignant neoplastic disease cells. It is a type of antimetabolite. Also called methotrexate sodium, MTX, and Rheumatrex. Gene is the functional and physical unit of genetic
    endowment passed from parent to offspring. Genes are pieces of DNA, and most
    genes contain the selective information for making a specific protein.
  • It’s possible to believe that, the peril factors for oral mucositis are broadly divided into two categories those influenced by patient status, and those related to the malignant neoplastic disease-treatment regimen.[1] Regimen is a handling plan that specifies the dosage, the schedule, and the duration of handling.
  • Seemingly, as well as the type of cancer being treated, the likelihood of developing oral mucositis varies depending on the site (i.e., situs), lifestyle and medical (i.e., medicinal, or medicinal) chronicle of the person.[2]
  • It’s apparent that, the combination of chemotherapy and irradiation increases the danger of developing severe oral mucositis.[2] Chemotherapy, treatment with drugs that wipe out malignant neoplastic disease cells. Radiation, energy released in the strain of atom or electromagnetic waves. Common sources of radiation include radon gas, cosmic rays from outer space (i.e., spatium), medical x-rays, and energy given off by a radioisotope (unstable
    form of a chemical element that releases radiation as it breaks downwards and
    becomes more stable).
  • It’s that, the type of chemotherapy used to treat the cancer will affect the likelihood of developing oral mucositis.[2]
  • As an example, therefore with radiation for head (i.e., caput) and neck (i.e., cervix, or collum) cancer, the symptoms of oral mucositis can continue for up to eight weeks.[2] Head and neck cancer, cancer that arises in the head or neck neighborhood (in the nasal (i.e., rhinal) cavity, sinuses, lips, mouth, salivary (i.e., sialic, or sialine) glands, throat (i.e.,
    gullet), or voice (i.e., vox) box [voice box]).
  • One can presume that, with each cycle of chemotherapy the risk of developing oral mucositis increases and the severity of the condition often worsens.[2] Condition is in medicine,
    a health trouble with certain characteristics or symptoms.
  • One can determine that, the sores and ulcers that line a mouth as a result of oral mucositis are at serious risk of exposure of infection.[2] Infection, invasion and times of germs in the body. Infections can occur in any region (i.e., regio) of the organic structure (i.e., structura) and can spread throughout the body. The germs may be bacteria, viruses, yeast, or fungi. They can
    cause a febricity and other problems, depending on where the infection occurs.
    When the body’s natural defense system is strong, it can oft fight the germs
    and prevent infection. Some cancer treatments can weaken the natural defense
    organisation.
  • Finally, one can view (i.e., projection), Oncology
    News Article – Reproductive factors and postmenopausal hormone use in relation to endometrial malignant neoplastic disease peril in the Nurses Health Study cohort 1976-2004 |2875807 presented here.[3] Hormone, one of many substances made by glands in the organic structure. Hormones distribute in the bloodstream and control the actions of certain cells or organs. Some hormones can also be made in the testing ground. Oncology is the written report of malignant neoplastic disease. Postmenopausal, having to perform with the time after menopause. Menopause ( change of life ) is the time in a adult female’s life when menstrual periods stop permanently. Endometrial, having to do with the endometrium (i.e., tunica mucosa uteri) (the level of tissue that lines the uterus (i.e., metra, or womb)). Cohort is a grouping of individuals who share a
    common trait, such as birth twelvemonth. In medicine, a cohort is a group that
    is part of a clinical tribulation or study and is observed over a period of
    time.

Terminology


Polymorphism

Occurrence in more than one form; existence in the same species or other natural group of more than one morphologic type


Lymph

A clear, transparent, sometimes faintly yellow and slightly opalescent fluid that is collected from the tissues throughout the body, flows in the lymphatic vessels (through the lymph nodes), and is eventually added to the venous blood circulation. Lymph consists of a clear liquid portion, varying numbers of white blood cells (chiefly lymphocytes), and a few red blood cells


Bloodstream

The flowing blood as it is encountered in the circulatory system, as distinguished from blood that has been removed from the circulatory system or sequestered in a part; thus, something added to the bloodstream may be expected to become distributed to all parts of the body through which blood is flowing.


Enzyme

A macromolecule that acts as a catalyst to induce chemical changes in other substances, while itself remaining apparently unchanged by the process. Enzymes, with the exception of those discovered long ago (pepsin, emulsin), are generally named by adding -ase to the name of the substrate on which the enzyme acts (glucosidase), the substance activated (hydrogenase), and/or the type of reaction (oxidoreductase, transferase, hydrolase, lyase, isomerase, ligase or synthetase these being the six main groups in the Enzyme Nomenclature Recommendations of the International Union of Biochemistry). For individual enzymes not listed below, see the specific name


Cycle

  1. A recurrent series of events.
  2. A recurring period of time.
  3. One successive compression and rarefaction of a wave,
    as of a sound wave.


Myelomatosis

A disease characterized by the occurrence of myeloma in various sites.


Spinal

  1. Relating to any spine or spinous process.
  2. Relating to the vertebral column


Reproductive

Relating to reproduction.


Adipose

Denoting fat.


Leukocytic

Pertaining to or characterized by leukocytes


Nasal

Relating to the nose


Immune system

an intricate complex of interrelated cellular, molecular, and genetic components that provides a defense, the immune response, against foreign organisms or substances and aberrant native cells.


Regimen

A program, including pharmacotherapy, which regulates aspects of one’s lifestyle for a hygienic or therapeutic purpose; a program of treatment; sometimes mistakenly called regime.


Mucositis

Inflammation of a mucous membrane.


Throat

  1. The fauces and pharynx.
  2. The anterior aspect of the neck.
  3. Any narrowed entrance into a hollow part


Digestive

Relating to digestion


Oncologist

A specialist in oncology.


Ostium

A small opening, especially one of entrance into a hollow organ or canal.


Fungi

A kingdom of eukaryotic organisms that grow in irregular masses, without roots, stems, or leaves, and are devoid of chlorophyll or other pigments capable of photosynthesis. Each organism (thallus) is unicellular to filamentous, and possesses branched somatic structures (hyphae) surrounded by cell walls containing glucan or chitin or both, and containing true nuclei. They reproduce sexually or asexually (spore formation), and may obtain nutrition from other living organisms as parasites or from dead organic matter as saprobes (saprophytes).


Brain

That part of the central nervous system contained within the cranium.


Radioisotope

An isotope that changes to a more stable state by emitting radiation.


Uterus

The hollow muscular organ in which the ootid is developed into the embryo and fetus; it is about 7.5-cm long in a nonpregnant woman; consists of a main portion (body) with an elongated lower part (cervix), at the extremity of which is the opening (external os). The upper rounded portion of the uterus, opposite the os, is the fundus, at each extremity of which is the horn marking the part where the uterine tube joins the uterus and through which the morula reaches the uterine cavity after leaving the uterine tube. The organ is passively supported in the pelvic cavity by the vagina and paracolpium and by the anteflexion and anteversion of the normal uterus, which places its mass superior to the bladder; it is actively supported by the tonic and phasic contraction of the muscles of the pelvic floor


Integument

  1. The enveloping membrane of the body; includes, in
    addition to the epidermis and dermis, all the derivatives of the epidermis,
    hairs, nails, sudoriferous and sebaceous glands, and mammary glands, as well
    as the subcutaneous tissue.
  2. The rind, capsule, or covering of any body or part


Cavity

  1. A hollow space; hole.
  2. Lay term for the loss of tooth structure from dental
    caries


Digestant

  1. Aiding digestion.
  2. An agent that favors or assists the process of
    digestion


Chemotherapy

Treatment of disease by means of chemical substances or drugs; usually used in reference to neoplastic disease.


Cartilage

A connective tissue characterized by its nonvascularity and firm consistency; consists of cells (chondrocytes), an interstitial matrix of fibers (collagen), and ground substance (proteoglycans). There are three kinds of cartilage hyaline cartilage, elastic cartilage, and fibrocartilage. Nonvascular, resilient, flexible connective tissue found primarily in joints, the walls of the thorax, and tubular structures (larynx, air passages, and ears); makes up most of the skeleton in early fetal life, but is slowly replaced by bone. For a gross anatomic description, see cartilago and its subentries


Endometrial

Relating to or composed of endometrium.


Endometrium

The mucous membrane comprising the inner layer of the uterine wall; it consists of a simple columnar epithelium and a lamina propria that contains simple tubular uterine glands. The structure, thickness, and state of the endometrium undergo marked change with the menstrual cycle. The blastocyst implants into the endometrium making the uterus gravid. If implantation does not occur, the superficial part of the endometrium is shed during the (hemorrhagic) menstrual phase of the uterine cycle


Infection

Invasion of the body with organisms that have the potential to cause disease.


Leukemia

Progressive proliferation of abnormal leukocytes found in hemopoietic tissues, other organs, and usually in the blood in increased numbers. Leukemia is classified by the dominant cell type, and by duration from onset to death. This occurs in acute leukemia within a few months in most cases, and is associated with acute symptoms including severe anemia, hemorrhages, and slight enlargement of lymph nodes or the spleen. The duration of chronic leukemia exceeds one year, with a gradual onset of symptoms of anemia or marked enlargement of spleen, liver, or lymph nodes


Bacteria

Plural of bacterium.


Neck

  1. Part of body by which the head is connected to the
    trunk, it extends from the base of the cranium to the top of the shoulders.
  2. In anatomy, any constricted portion having a fancied
    resemblance to the neck of an animal.
  3. The germinative portion of an adult tapeworm, that
    develops the segments or proglottids; the region of cestode segmentation
    behind the scolex


Risk factor

a characteristic statistically associated with, although not necessarily causally related to, an increased risk of morbidity or mortality, smoking as a risk factor for heart disease.


Menstrual

Relating to the menses.


Cervix

Any necklike structure


Oncology

The study or science dealing with the physical, chemical, and biologic properties and features of neoplasms, including causation, pathogenesis, and treatment.


Myeloma

  1. A tumor composed of cells derived from hemopoietic
    tissues of the bone marrow.
  2. A plasma cell tumor.


Sperm

The male gamete or sex cell that contains the genetic information to be transmitted by the male, exhibits autokinesia, and is able to effect zygosis with an oocyte. The human sperm is composed of a head and a tail, the tail being divisible into a neck, a middle piece, a principal piece, and an end piece; the head, 46 mcm in length, is a broadly oval, flattened body containing the nucleus; the tail is about 55 mcm in length


Neoplastic

Pertaining to or characterized by neoplasia, or containing a neoplasm.


Oral

Relating to the mouth.


Salivary

Relating to saliva


Malignancy

The property or condition of being malignant.


Cohort

  1. Component of the population born during a particular
    period and identified by period of birth so that its characteristics can be
    ascertained as it enters successive time and age periods.
  2. Any designated group followed or traced over a
    period, as in an epidemiologic cohort study.


Medicinal

Relating to medicine having curative properties


Methotrexate

A folic acid antagonist used as an antineoplastic agent; used to treat psoriasis and rheumatoid arthritis


Rheumatoid

Resembling rheumatoid arthritis in one or more features.


Lymphoma

Any neoplasm of lymphoid or reticuloendothelial tissues; in general use, synonymous with malignant lymphoma; present as apparently solid tumors composed of cells that appear primitive or resemble lymphocytes, plasma cells, or histiocytes. Lymphomas appear most frequently in the lymph nodes, spleen, or other normal sites of lymphoreticular cells; may invade other organs or manifest as leukemia. Lymphomas are now classified by histology, immunophenotype, and cytogenetic analysis, according to cell of orgin (B or T cells) and degree of maturation. The current World Health Organization (WHO) classification of lymphoid neoplasms is based on the Revised European-American Lymphoma (REAL) classification and effectively replaces older schemes such as the Working Formulation and Rappaport classification, which were based solely on morphology.


Rheumatism

  1. Obsolete term for rheumatic fever.
  2. Indefinite term applied to various conditions with
    pain or other symptoms of articular origin or related to other elements of the
    musculoskeletal system.


Cosmic rays

high-velocity particles of enormous energies, bombarding earth from outer space; the primary radiation consists of protons and more complex atomic nuclei that, on striking the atmosphere, give rise to neutrons, mesons, and other less energetic secondary radiation.


Germs

microphobia.


Psoriasis

A common multifactorial inherited condition characterized by the eruption of circumscribed, discrete and confluent, reddish, silvery-scaled maculopapules; the lesions occur predominantly on the elbows, knees, scalp, and trunk, and microscopically show characteristic parakeratosis and elongation of rete ridges with shortening of epidermal keratinocyte transit time due to decreased cyclic guanosine monophosphate.


Atom

Formerly considered the ultimate particle of an element, believed to be as indivisible as its name indicates. Discovery of radioactivity demonstrated the existence of subatomic particles, notably protons, neutrons, and electrons, the first two making up most of the mass of the atomic nucleus. It is now known that subatomic particles are further classified into hadrons, leptons, and quarks.


Menopause

Permanent cessation of the menses due to ovarian failure; termination of the menstrual life.


Ramification

The process of dividing into a branchlike pattern.


Cavernous space

an anatomic cavity with many interconnecting chambers


Arthritis

Inflammation of a joint or a state characterized by inflammation of the joints


Hormone

A chemical substance, formed in one organ or part of the body and carried in the blood to another organ or part where they exert functional effects; depending on the specificity of their effects, hormones can alter the functional activity, and sometimes the structure, of just one organ or tissue or various numbers of them. Various hormones are formed by ductless glands, but molecules such as secretin, cholecystokinin/somatostatin, formed in the gastrointestinal tract, by definition are also hormones. The definition of hormone has been recently extended to chemical substances formed by cells and acting on neighboring cells (paracrine function) or the same cells that produce them (autocrine function). For hormones not listed below, see specific names.


Medicine

  1. A drug.
  2. The art of preventing or curing disease; the science
    concerned with disease in all its relations.
  3. The study and treatment of general diseases or those
    affecting the internal parts of the body, especially those not usually
    requiring surgical intervention.


Radiation

radiophobia.


Malignant

  1. occurring in severe form, and frequently fatal;
    tending to become worse and leading to an ingravescent course.
  2. In reference to a neoplasm, having the property of
    locally invasive and destructive growth and metastasis.


Cistron

  1. The smallest functional unit of heritability; a
    length of chromosomal DNA associated with a single biochemical function. Under
    classical concepts, a gene might consist of more than one cistron; in modern
    molecular biology, the cistron is essentially equivalent to the structural
    gene.
  2. The genetic unit defined by the cis/trans test.


Schedule

A procedural plan for a proposed objective, especially the sequence and time allotted for each item or operation required for its completion.


Reductase

An enzyme that catalyzes a reduction; because all enzymes catalyze reactions in either direction, any reductase can, under the proper conditions, behave as an oxidase and vice versa, hence the term oxidoreductase. For individual reductases, see the specific names


Postmenopausal

Relating to the period following the menopause.


Dr.

Abbreviation for doctor.


Dna

Abbreviation for deoxyribonucleic acid. For terms bearing this abbreviation, see subentries under deoxyribonucleic acid.


Head

  1. The upper or anterior extremity of the animal body,
    containing the brain and the organs of sight, hearing, taste, and smell.
  2. The upper, anterior, or larger extremity, expanded or
    rounded, of any body, organ, or other anatomic structure.
  3. The rounded extremity of a bone.
  4. That end of a muscle that is attached to the less
    movable part of the skeleton


Irradiation

  1. The subjective enlargement of a bright object seen
    against a dark background.
  2. Exposure to the action of electromagnetic radiation
    (heat, light, x-rays).
  3. The spreading of nervous impulses from one area in
    the brain or cord, or from a tract, to another tract.


Genetic

Pertaining to genetics; genetical.


Chondrus

The plant Chondrus crispus, Fucus crispus, or Gigartina mamillosa (family Gigartinaceae); a demulcent in chronic and intestinal disorders


Medical

Relating to medicine or the practice of medicine


Mucosa

A mucous tissue lining various tubular structures consisting of epithelium, lamina propria, and, in the digestive tract, a layer of smooth muscle (muscularis mucosae)


Cavernous

Relating to a cavern or a cavity; containing many cavities.


Methylene

The moiety, CH2.


Nervous

  1. Relating to a nerve or the nerves.
  2. Easily excited or agitated; suffering from mental or
    emotional instability; tense or anxious.
  3. Formerly, denoting a temperament characterized by
    excessive mental and physical alertness, rapid pulse, excitability, often
    volubility, but not always fixity of purpose.


Fatty tissue

in some animals, brown fat


Radiotherapist

One who practices radiotherapy or is versed in radiotherapeutics


Sarcoma

A connective tissue neoplasm, usually highly malignant, formed by proliferation of mesodermal cells.


Antimetabolite

A substance that competes with, replaces, or antagonizes a particular metabolite; ethionine is an antimetabolite of methionine.

Related Material

  1. Oral Mucositis in Cancer Patients: Treatment Update – Chemotherapy Advisor
  2. Oral Mucositis: frequently asked questions
  3. Oncology News Article | Reproductive factors and postmenopausal hormone use in relation to endometrial cancer risk in the Nurses Health Study cohort 1976-2004 |2875807
  4. Oral Mucositis | American Academy of Oral Medicine (AAOM)
  5. What causes Oral Mucositis? | Caphosol for oral mucositis and dry mouth from cancer therapy

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